Montia Daniels
As a Black queer woman, Mahogany Mckoy was averse to the preachings she experienced as a child that being queer and certainly transgender was a sin. As a child, she didn’t understand why this was a factor and walked away … Read more
As a Black queer woman, Mahogany Mckoy was averse to the preachings she experienced as a child that being queer and certainly transgender was a sin. As a child, she didn’t understand why this was a factor and walked away … Read more
TCF4 is associated with a range of neurodevelopmental and psychiatric disorders, including autism, schizophrenia, and Pitt-Hopkins Syndrome (PTHS). Although necessary to decipher TCF4 biology and guide future therapeutic approaches, our knowledge of TCF4 expression in the developing brain is still … Read more
Given the scarcity of current research addressing the needs of Hispanic children with autism and their families, the purpose of the current study was to examine the impact of ecological microsystems on outcomes for Hispanic students with autism based on … Read more
Pitt Hopkins Syndrome (PTHS) is a genetic disorder resulting from a mutation or deletion of the TCF4 gene. Individuals with PTHS have different levels of intellectual disability, speech impairments, seizures, breathing anomalies, and gastrointestinal problems. Despite TCF4 clinical importance, its … Read more
Recent multi-omic efforts have facilitated the discovery of unannotated small open reading frame encoded polypeptides (SEPs). SEPs are small proteins (< 50 amino acids in length) representing an underexplored class of biomolecules due to the lack of genome prediction software … Read more
Despite their size, galaxies are not the largest structures in the universe. Unless they are isolated, gravity allows galaxies to congregate at different scales in groups, clusters, and superclusters, which make up the large scale structure of the universe. A … Read more
Partial correlation coefficients are used to determine the strength of an association between two variables while controlling for the effects of confounding variables. Partial correlations range between -1 and 1 and can be computed in the presence of continuous or … Read more
Approximately 37.7 million people globally were living with HIV in 2020. Although sub-Saharan Africa has about 14% of the global population, it is home to two thirds (67%) of people living with HIV. Due to this disproportionate burden of HIV … Read more
Migraine, characterized by calcitonin gene-related peptide (CGRP) upregulation in the cerebral circulation, impacts 15% of the global population, is the second leading cause of years lived with disability, and impacts women 3 times more frequently than men (1,2). Recent studies … Read more
Mutations in the KRAS oncogene are among the most frequent driver events in human cancers. Following decades of failed efforts, KRAS was considered ‘undruggable’. However, recent efforts in covalently targeting KRAS mutants harboring a G12C mutation has produced the first … Read more