Historically, cellular morphology has been described using non-specific qualitative language and example images rather than quantitative data, limiting its investigation. The novel technologies ilastik and CellProfiler have emerged to solve this issue and allow for the high-throughput analysis of images … Read more

The COVID-19 pandemic has served as a major stressor, impacting millions of individuals across the world. It is likely the stress of the pandemic has had a uniquely strong impact on parents. Over the last year, substantial research has emerged … Read more

Nicotine is a highly addictive chemical that has traditionally been consumed by smoking cigarettes. Due to the introduction of new technology such as electronic cigarettes, nicotine vaping has surged in popularity. The rising popularity of vaping necessitates the development of … Read more

SWI/SNF is a nucleosome remodeling complex that is found in all cells of the body. SWI/SNF plays a crucial role in changing nucleosome spacing and thus allowing transcription to be carried on. In addition, they have tumor suppression activity where … Read more

Phagocytosis is an essential part of the immune system in which phagocytes engulf foreign bodies. Engulfment relies on force-dependent reorganization of a cell’s cytoskeleton which is primarily made up of actin. Actin undergoes a complicated orchestration whereby polymerizing and restructuring … Read more

Several epidemiological studies have found that heavy alcohol use may increase the risk of developing Alzheimer’s disease (AD), although the mechanisms behind this link are unclear. The increase in neuroinflammation seen during alcohol abuse and AD may drive this connection, … Read more

Urban and rural residents have different food environments and different resources available to them. Research has shown that healthy foods are more likely to be more expensive in rural areas and less accessible. SNAP beneficiaries may face particular barriers from … Read more

Background. Approximately 2.4 million well water users in North Carolina (NC) are vulnerable to metal contamination because they are not protected by the Environmental Protection Agency’s (EPA) Safe Drinking Water Act (USGS, 2018). The established relationship between social and economic … Read more

Environmental chemicals amount to a large portion of the exposures an individual experiences over their lifetime. Exposure to per- and poly- fluoroalkyl substances (PFAS) have been shown to negatively affect the health of vulnerable populations such as pregnant women and … Read more

Ewing Sarcoma is a pediatric bone cancer driven by a chromosomal translocation, which in some cases leads to the expression on an oncoprotein, EWS-FLI1. EWS-FLI1 drives the cancer cells by altering the transcription program and creating aberrantly accessible regions of … Read more